Alcohols and polyols
- (1)
- (55)
- (343)
- (39)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
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- (156)
- (1)
- (64)
- (27)
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- (1)
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- (30)
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- (20)
- (10)
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- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (12)
- (145)
- (116)
- (7)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
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- (1)
- (2)
- (2)
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- (1)
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- (5)
- (2)
- (2)
- (1)
- (10)
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- (1)
- (9)
- (1)
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- (5)
- (1)
- (1)
- (1)
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- (1)
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- (1)
- (1)
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- (2)
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- (1)
- (1)
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- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
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- (2)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (2)
- (2)
- (1)
- (1)
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- (4)
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- (1)
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- (1)
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- (27)
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- (1)
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- (7)
- (1)
- (18)
- (16)
- (1)
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- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
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- (16)
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- (21)
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- (1)
- (67)
- (1)
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- (7)
- (4)
- (85)
- (1)
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- (72)
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- (21)
- (279)
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- (1)
- (6)
- (278)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
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- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
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- (2)
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- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
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- (33)
- (2)
- (31)
- (39)
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Filtered Search Results
Medchemexpress LLC GGTI-2154 (hydrochloride) | 478908-50-8 | 98.1% | 456.97 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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GGTI-2154 hydrochloride is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. It demonstrates over 200-fold selectivity for GGTase I compared to FTase (IC50=5600 nM). This product is suitable for cancer research. It is for research use only and not sold to patients.
- Potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) with an IC50 of 21 nM.
- Shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM).
- Can be used for cancer research.
- Induces breast tumor regression in MMTV-ν-Ha-Ras transgenic mice (100 mg/kg/day; s.c. for 14 days).
- Inhibits A-549 tumor growth in nude mice by 60% (50 mg/kg/day; i.p. for 50 days).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Riviciclib hydrochloride | 920113-03-7 | 99.08% | 438.30 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Riviciclib hydrochloride is a potent cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively. This compound shows antitumor activity on cisplatin-resistant cells.
- IC50 & Target information available
- In vitro studies show activity in various cancer cell lines
- In vivo studies demonstrate significant inhibition of tumor growth
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with high affinity for hORL-1 (Ki = 0.33 nM). It demonstrates selectivity for μ-, κ-, and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.
- Potent ORL-1 antagonist with high affinity.
- Exhibits selectivity for μ-, κ-, and δ-receptors.
- Effectively antagonizes pronociceptive action of Nociceptin.
- Demonstrates antihyperalgesic effects in animal models.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 25 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices and has various in vivo effects, including the prevention of certain tumors and reduction of parasite burden.
- Potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
- Inhibits estrogen production with an IC50 of 0.03 μM.
- Inhibits progesterone production with an IC50 of 120 μM.
- Inhibits aromatase-mediated uterine hypertrophy in immature female rats with an oral ED50 of 0.03 mg/kg.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows spontaneous development of pituitary pars distalis adenomas.
- Reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
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Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 5 MG
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Alfuzosin hydrochloride (SL 77499-10) is an orally active, selective, and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination, and can be used in the study of benign prostatic hyperplasia (BPH).
- Orally active, selective, and competitive α1-adrenoceptor antagonist.
- Relaxes the muscles of the prostate and bladder neck, aiding in urination.
- Used in the study of benign prostatic hyperplasia (BPH).
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Medchemexpress LLC Moexipril hydrochloride | 82586-52-5 | 98.4% | 100 MG
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Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). It exhibits antihypertensive and neuroprotective effects. This compound is for research use only and not sold to patients.
- Inhibits angiotensin-converting enzyme (ACE)
- Exhibits antihypertensive and neuroprotective effects
- Significantly reduces the percentage of damaged neurons
- Attenuates Fe2+/3+-induced neurotoxicity
- Exhibits dose-dependent and antihypertensive effects in renal hypertensive rats, spontaneously hypertensive rats, and perinephritic hypertensive dogs
- Significantly reduces the infarct area on the mouse brain surface
- Significantly attenuates the cortical infarct volume in rats
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Medchemexpress LLC 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1) | 15622-65-8 | 99.8% | 1 ML
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Molindone hydrochloride is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. It exhibits antipsychotic and antidepressant-like activities, suppressing spontaneous locomotion and antagonizing apomorphine-induced emesis. It can be used for research related to neurological diseases.
- Orally active and brain-penetrant dopamine D2/D5 receptor antagonist.
- Shows antipsychotic and antidepressant-like activities.
- Suppresses spontaneous locomotion.
- Antagonizes apomorphine-induced emesis.
- Can be used for the research of neurological disease.
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Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 500 MG
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Flavoxate hydrochloride is an orally active L-type Ca2+ channel inhibitor and antispasmodic. It inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors.
- Relaxes bladder smooth muscle
- Inhibits isovolumetric rhythmic contractions
- Increases bladder capacity
- Alleviates symptoms of urgent urination frequency and pollakiuria
- Suitable for research on overactive bladder and related voiding dysfunctions
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Medchemexpress LLC (R)-Preclamol hydrochloride | 89874-80-6 | 98.0% | 255.78 | 50 MG
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(R)-Preclamol hydrochloride ((+)-3-PPP hydrochloride) is the R-enantiomer of Preclamol hydrochloride. It is a DA agonist with autoreceptor as well as postsynaptic receptor stimulatory properties.
- Purity of 98.0%
- CAS number 89874-80-6
- Molecular weight of 255.78
- Solid appearance
- Off-white to light yellow color
- Recommended storage at 4°C, sealed and away from moisture
- Soluble in DMSO at 100 mg/mL
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Medchemexpress LLC 1-Piperazinebutanol, α-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-, hydrochloride (1:1) | 105565-55-7 | 98.0% | 384.85 | 25 MG
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1-Piperazinebutanol, α-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-, hydrochloride (1:1) | 105565-55-7 | 98.0% | 384.85 | 25 MG
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Medchemexpress LLC SGK1-IN-3 hydrochloride | 00-00-0 | 96.7% | C23H21Cl3N6O3S | 10MG
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SGK1-IN-3 hydrochloride is a research-grade small-molecule inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1), reported to inhibit SGK1 with an IC50 of <1 μM. Supplied as the hydrochloride salt, it is intended for biochemical and cell-based research applications, including studies of signaling pathways related to osteoarthritis.
- Potent SGK1 inhibition (IC50 <1 μM).
- Hydrochloride salt form for improved solubility.
- Suitable for biochemical and cell-based assays.
- High reported purity (~96.7%).
- Available in small research pack sizes for laboratory use.
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Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 100 MG
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Adrogolide hydrochloride is a chemically stable prodrug that is converted rapidly in plasma to the dopamine D1 receptor agonist A-86929 and is used in preclinical research on Parkinson's disease and dopaminergic signaling. It is supplied as a white to off-white solid with documented purity, molecular weight, solubility, and storage recommendations.
- High purity: 99.6% (reported)
- Molecular weight 435.96
- Chemical formula C22H26ClNO4S
- Soluble in DMSO (≈66.7 mg/mL with warming)
- Documented in vivo formulations for vehicle preparation
- Stable prodrug that converts to A-86929 in plasma
- Store at room temperature; in solvent store at -80°C for long term
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Medchemexpress LLC Fradafiban hydrochloride | 00-00-0 | MFCD00919205 | 100.0% | 403.86 g·mol⁻¹ | C20H22ClN3O4 | 1 MG
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Fradafiban hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist that binds the human GP IIb/IIIa complex (Kd = 148 nM) and inhibits platelet aggregation in vitro. It is a nonpeptide mimetic of the arginine-glycine-aspartic acid (RGD) recognition sequence, supplied as a white to off-white solid for research use.
- Binds human platelet GP IIb/IIIa with a reported Kd of 148 nM.
- Inhibits platelet aggregation in vitro.
- Nonpeptide RGD mimetic, suitable for mechanistic studies.
- High purity (reported 99.96%).
- White to off-white solid, convenient for handling and storage.
- Available in small research sizes (1 mg, 5 mg, 10 mg, 50 mg, 100 mg).
- Molecular weight 403.86 g·mol⁻¹; molecular formula C20H22ClN3O4.
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Medchemexpress LLC Caroverine hydrochloride | 55750-05-5 | MFCD01684929 | 98.9% | 401.93 g/mol | C22H28ClN3O2 | 5 MG
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Caroverine hydrochloride is a research reagent that acts as a potent, competitive, and reversible antagonist of NMDA and AMPA glutamate receptors. It also exhibits antioxidant and calcium-blocking activity with vasorelaxant effects, and is used in studies such as inner-ear tinnitus research. The compound is supplied as a white to off-white solid with high purity.
- Antagonist of NMDA and AMPA glutamate receptors.
- Exhibits antioxidant and calcium-blocking activity.
- Displays vasorelaxant effects useful in vascular studies.
- Suitable for research into inner-ear tinnitus mechanisms.
- High purity for research applications (98.9%).
- White to off-white solid, stable when stored sealed and protected from moisture.
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Medchemexpress LLC Prx-07034 hydrochloride | 903580-39-2 | 99.0% | C21H29Cl2N3O4S | 25 MG
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PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki of 4-8 nM and IC50 of 19 nM. Intended for research on enhancing working memory and cognitive flexibility, it shows significant 5-HT6 receptor selectivity (>100-fold over 68 other GPCRs, ion channels, and transporters). It also inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors. In vivo studies in rats demonstrated enhanced delayed spontaneous alternation and improved cognitive strategy switching.
- Highly selective and potent 5-HT6 receptor antagonist
- Ki of 4-8 nM and IC50 of 19 nM for 5-HT6 receptor
- Enhances working memory and cognitive flexibility
- >100-fold selectivity over 68 other GPCRs, ion channels, and transporters
- Inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors
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